Linoleic Acid: A Milestone in Brain Evolution? From Bacteria, Fungi and Plants to Animal and Human Beings

DOI: 10.14673/HE2015341011
Published in Human Evolution – Vol. 30 – n.3-4 – 2015

Key words: Linoleic Acid, humans, animals, bacteria, plants, fungi, brain, symmetry breaking, evolution.

Abstract
Here we discuss the role of Linoleic Acid (LA-C18:2 n-6), a fatty acid considered essential for life, which has always been present during evolution in bacteria, fungi, plants, animals and human beings. There is evidence of similar concentrations of Linoleic Acid (close to zero) in the brains of humans and animals in all stages of life. Moreover, observations of Linoleic Acid in bacteria, plants and fungi indicate that it has been an important milestone throughout the course of evolution. With regard to fungi, we note the presence of Arachidonic Acid and cholesterol in its early development. Finally, we consider some aspects of cholesterol and oxygen during evolution and their relationship with Linoleic Acid.

Cocchi, M.
Minuto, C.
“Paolo Sotgiu” Institute for Research
in Quantitative & Quantum Psychiatry & Cardiology, LUdeS, Lugano, Switzerland.
Department of Veterinary Medical Sciences, University of Bologna, Bologna, Italy.
E-mail: massimo.cocchi@unibo.it

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